Suddenly I am inundated with HKeys. Ray.s site says they are removed but come back almost immeadiatly.  How can I get rid of them permanetly, and where did they come from??

   I don't understand.  How are you inundated with HKeys?  Where are you seeing them?  Are you talking about using RegVac?  A1Click?  Please explain.

Each time I use Reg Vac. there are over 250 items show up under HKEY-all users.
Reg Vac shows they are deleted, but they always come back???
If I go to RUn-regedit they show up there.  Never had them before???
Can I delete them under regedit????

Sorry I don't have Reg Vac. I have A1 Pc Cleaner.

   You probably did not use the Registry Cleaner in A1Click before.  That is why they did not show up before.  The Registry Cleaner just empties certain trash sections in the registry.  So what you are experiencing is normal.  Most of the items are safe to remove.  The User Assist items can cause problems if removed.  The User Assist sections are automatically refilled by Windows and so that could explain why they show right back up.
   You can uncheck the Registry Cleaner part so that it is not used.
   The Registry Cleaner in A1Click does a fraction of what RegVac (http://superwin.com/regvac.htm) does.  RegVac does a better and safer job of cleaning the registry.

If I purchase Reg Vac, do I delete Reg Cleaner A1??

   A1Click is not a registry cleaner.  It is a drive cleaner.  A1Click does have a minimal registry cleaner in it for removing tracks, but A1Click mainly cleans junk files from the hard drive.  RegVac does not clean the drive.  RegVac cleans the registry.  So RegVac does one thing and A1Click does another.
   If you purchase RegVac, you should still use A1Click but I would suggest that you uncheck the Registry Cleaner part of it.