I have two cronic annoying errors they are not life or death just bothersome.

The first is everytime I start windows or reboot for that matter I get the same error not fatal but annoying and I have to wait until windows is loaded and the desktop is on to close this message (window) ( ISSAS.EXE could not be found)

And the second one is with Yahoo.com ( my email site) when I click on any link most of the time I get: Page can't open because Page can not be found??? and when I refresh a few times then it opens!!!
Do you guys have any suggestions???

ISSAS is a particularly nasty Trojan/virus.  This is not something that A1 cleaner is designed to remove.  Download the free versions of Adaware and Spybot and run them repeatedly in safe mode.  This particular virus tends to rewrite to itself to different locations and requires multiple runs of these programs to totally eradicate it.

Best of luck.