A1 Cleaner creates a couple or more zip files for retoring purposes.  Though these can be deleted after a few days they are pretty massive files and as they are placed in the A1 Cleaner folder, that means in my case that the drive is almost full when the scan has finished its job.  Through "Change Settings" I cannot see any way in which I can select a folder on another partition into which the program would then create the zips it needs for a restore.  Is it not possible to change that back up file folder?

   No.  The backup folder is always a subfolder of the A1Click folder.
   You could move A1Click.